Active Clinical Trials



Optimal treatment for women with a Persisting Pregnancy of Unknown Location- a Randomization Clinical Trial of women at risk for an ectopic pregnancy: Active Treatment versus Expectant Management (No Treatment) The "ACTorNOT TRIAL"

This is a randomized controlled trial to compare three currently available management strategies for women with a persisting pregnancy of unknown location (PPUL), which makes them at-risk for ectopic pregnancy.  This is for stable women with a confirmed PPUL to be randomized to one of three strategies:

  1. Uterine evacuation followed by methotrexate (MTX) for some (those that have evidence of a non-visualized ectopic pregnancy)
  2. Empiric treatment with MTX for all
  3. Expectant management 

Recruiting from clinical population only


Principal Investigator:
Dr. Kurt Barnhart, MD, MSCE


Study Coordinator:
Ashley Singer
215-615-4201 listing

Clinical Trials Now Recruiting!

Active Clinical Trials

Fertility and the BRCA gene

Studies on the Epigenetic Regulation of Human Pregnancy in  Fertile and Infertile Couples and Placental Parameters Sub-Study


Paid research study seeking healthy women who are not at risk for pregnancy

Infertility study

Non-hormonal intrauterine device